If you have an uncomplicated, ordinary urinary tract infection, consider taking D-mannose as a form of natural therapy for bladder infections. D-mannose is a simple sugar just like glucose but it is absorbed much more slowly in the intestinal tract. Once absorbed, it doesn’t go to glycogen storage like glucose does but instead enters the bloodstream and goes into the urinary tract via the kidneys.

The lining of the bladder is made of polysaccharide molecules that bacteria stick to and infect the bladder. When D-mannose is introduced into the bladder, the bacteria preferentially adhere to the free D-mannose molecules and are flushed from the bladder when you void. D-mannose has the potential to treat bladder infections about 80 to 90 percent of the time. In addition, it works in the GI tract by adhering to the bad bacteria in the gut and flushing out those bacteria as well. Yeast can be removed from the GI tract this way. It is a good idea to follow this treatment up with probiotics that can replace the bad bacteria that were removed from the GI tract. Bacteria from the GI tract are the bacteria that cause bladder infections, so it pays to have good bacteria in the colon as well.

You can take a supplement of D-mannose from a health food store or you can eat a lot of cranberries, blueberries, peaches, apples, and oranges. Each of these fruits contains a great deal of D-mannose and is effective in curing ordinary cases of bladder infection. D-mannose is safe for diabetics to take and is perfectly safe for use in pregnancy. Remember, D-mannose does not kill bacteria but is instead a magnet that attracts the bacteria away from the bladder wall and flushes out the bacteria during voiding.

There is scientific evidence that D-mannose has been effective in curing UTIs. In one study, a total of 43 women and 18 men with recurrent UTIs were treated with D-mannose therapy. Of the females studied, a total of 24 were found to have positive urine cultures, most with E. coli as the cause, but some having Klebsiella or mixed bacteria. Two scoops of D-mannose powder were given to the patients with the UTIs for a total of one week. Half returned for follow up cultures and three-fourths of these had negative cultures. All patients had improvement in their symptoms. Of the women in the study, 71 percent reported the absence of symptoms after a week.

Some women who did not have positive cultures were diagnosed with interstitial cystitis or painful bladder syndrome. These women were treated with two scoops per day of D-mannose as well. Of these patients, 94 percent reported improvement in their symptoms and a total of 80 percent of women were completely symptom-free by the end of one week.

Of the men, only ten had culture-positive urinary tract infections. Most had complicated UTIs, such as UTIs caused by catheters, neurogenic bladder, or suprapubic catheters. This group generally had E. coli cystitis and was treated with D-mannose. There was less effective in this group of patients, in part due to the complications noted in the patient group.






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